Parkinson’s Disease
Parkinson’s disease is a neurological disorder that involves the degeneration of the dopamine-producing neurons in the brain. It primarily impacts the section of the brain called the substantia nigra.
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Signs and Symptoms
The most common early signs of Parkinson’s disease include the following:
- Tremor that occurs while at rest and particularly on one side of the body
- Changes in handwriting, such as the words or letters becoming smaller or more crowded
- Loss of smell
- Difficulty sleeping
- Difficulty with moving or walking due to stiffness in the body, especially in the arms or legs
- Constipation
- Changes in voice, such as a softening or lowering of the voice
- Persistent unhappy look on the face called facial masking
- Dizziness or loss of consciousness
- Changes in posture, such as slouching, hunching over or stooping
Potential Causes
Researchers are unsure why these neurons begin to degenerate. There may be some genetic factors which make a person more susceptible to Parkinson’s disease, but more research is needed in this area.
Diagnosis
Many other conditions can cause the same symptoms, so it is important to check with your doctor for an accurate diagnosis. Only a doctor experienced in recognizing the exact combination of symptoms that indicate Parkinson’s disease can make a firm diagnosis.
Diagnosis starts with a physical exam and medical history. Other procedures and tests may be needed to diagnose, including a detailed neurological exam and blood and imaging tests to rule out other potential causes and disorders.
Treatment Options
There are a few treatments to help manage the symptoms of Parkinson’s disease:
- Medication to help with symptoms. These medications usually work to increase dopamine in the brain.
- Deep brain stimulation This procedure may be recommended because, over time, medications may become less effective. Before quality of life declines significantly, we recommend surgery for select patients. Asleep deep brain stimulator surgery is the best way to have your surgery performed with modern computer technology. One to two weeks before your surgery, you will have a special MRI of your brain at the same hospital as your surgery, along with an appointment to make sure you can safely go to sleep with anesthesia for the surgeries. Once asleep you will have two very thin electrodes placed in your brain. There will be a CT scan done before you wake up to confirm the accuracy of the leads, and then your first surgery will finish. You will stay in the hospital one night and go home the next day. One week later, you will have an outpatient surgery where the generator, also known as the “battery,” will be placed below your collar bone (where a pacemaker goes). You will go home the same day, and the battery will be turned on in your neurologist’s office.
Frequently Asked Questions
Parkinson’s disease is a progressive neurological condition caused by the loss of dopamine-producing cells in the brain. It’s a diagnosis that carries real emotional weight for both patients and their families, and our goal here is to talk you through each stage of care.
While there is currently no cure for Parkinson’s disease, treatment can effectively manage symptoms and help maintain independence and quality of life. Early in the disease, most patients benefit from medications that improve dopamine signaling, along with physical, occupational, and speech therapy to preserve mobility, communication, and daily function. As symptoms progress or become less responsive to medication, advanced treatments such as deep brain stimulation (DBS) may be recommended as part of a comprehensive Parkinson’s disease treatment plan tailored to each patient’s needs.
Common symptoms include resting tremor (e.g., shaking in the hands, arms, or legs at rest), muscle rigidity, slowed movement (also known as bradykinesia), and difficulty with balance or walking. Non-motor symptoms such as sleep disruption, cognitive changes, or trouble swallowing/speaking can also indicate progression and the need for specialist examination. If symptoms are interfering with daily life, or you’re wondering whether your movement disorder treatment should include surgical options, it’s time to seek a specialist evaluation. Early consultation at Goodman Campbell helps ensure you don’t miss the window for advanced treatments like DBS surgery.
Deep brain stimulation (DBS) is a surgical procedure that uses precisely placed electrodes in areas of the brain that control movement. These electrodes connect to a small implanted device (similar to a pacemaker) near the collarbone that delivers controlled electrical pulses to help normalize the abnormal brain activity responsible for tremor, stiffness, and slowed movement. Goodman Campbell’s functional neurosurgeon in Indianapolis treats patients with Parkinson’s disease using advanced therapies such as deep brain stimulation (DBS), which is performed under general anesthesia. Advances in computer-guided imaging and targeting have significantly improved both precision and outcomes compared to earlier techniques, which required patients to be awake during the procedure. DBS has been used safely for more than 30 years and is both adjustable and reversible, allowing us to fine-tune treatment as your needs change.
DBS is typically recommended for individuals who have lived with Parkinson’s disease for four or more years, have seen benefit from dopamine-based therapies, and are now dealing with motor symptoms that are becoming difficult to manage. Strong candidates are generally in good overall health and have not experienced significant cognitive decline or severe balance issues. Determining eligibility involves a comprehensive presurgical assessment by a multidisciplinary team — including a neurologist and a functional neurosurgeon — using movement evaluations, brain imaging, and neuropsychological testing. Because DBS is not appropriate for everyone, our focus is on identifying the treatment path that will most meaningfully improve each patient’s quality of life.
The process begins with a detailed evaluation completed weeks before surgery, including a specialized MRI, movement assessments, and medical clearance to confirm candidacy and guide surgical planning. During lead placement, electrodes are implanted in the brain at the hospital, typically followed within weeks by a separate outpatient procedure to place the neurostimulator under the skin of the chest. After activation, the device is carefully programmed over multiple follow-up visits to achieve the best balance between symptom relief and side effects, a process that often spans several months. Over the long term, DBS settings can be adjusted as symptoms or goals evolve, giving patients ongoing access to a care team experienced in long-term outcomes.
Neurologists specialize in diagnosing and managing Parkinson’s disease, while functional neurosurgeons bring a distinct level of training focused on surgically modifying or restoring how the nervous system functions. When surgery enters the conversation, the experience and expertise of the surgical team directly impact outcomes. When considering surgical care, the expertise of the neurosurgical team is just as important as the procedure itself.
Deep brain stimulation is FDA-approved and covered by most major insurance plans, although coverage details vary. To discuss your situation, we encourage you to request an appointment with Goodman Campbell functional neurosurgeon Mark Hoeprich, MD, who sees patients at Ascension St. Vincent – Indianapolis Functional Neurosurgery. To request an appointment with Dr. Hoeprich, call 317-338-9660.
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