Research and Clinical Trials

Our Mission Includes Research

Goodman Campbell physicians have a dedicated interest in clinical research related to neurologic conditions. Our physician specialists and research team actively pursue and are involved in a variety of clinical trials. From infants to adults, we are researching areas including the brain, spine, stroke and interventional pain management. Our research nurses and staff are experts in their areas of study and in the clinical trials we are conducting. Please explore our research options below and contact us at 317-396-1300 with any questions.

Current Clinical Trials

A Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 for Patients with Brain Contusion (ASTRAL)
Investigators: Richard B. Rodgers, MD; Charles Kulwin, MD; Eric Horn, MD PhD
Sponsor: Biogen
Focus: Patients in the hospital with acute brain contusion able to be enrolled within six hours of injury will be considered for this study. The primary goal of this trial is to evaluate an investigational drug (BIIB093) in the treatment of brain contusion. Identifier: NCT03954041

Differential-Target Multiplex Low Energy Spinal Cord Stimulation (DTM-LE SCS) Study
Investigator: Todd Schmidt, MD
Sponsor: Medtronic
Focus: Patients with chronic pain undergoing evaluation for placement of an implantable Medtronic Intellis AdaptiveStim Neurostimulation System are eligible for consideration in this study. The study seeks to evaluate programming parameters within the neurostimulation system. Identifier: NCT04601454

ENRICH: Early Minimally-invasive Removal of Intracerebral Hemorrhage (ICH)
Investigators: Charles Kulwin, MD; Richard B. Rodgers, MD
Sponsor: Nico Corporation
Focus: Patients in the hospital due to spontaneous intracerebral hemorrhage able to be enrolled within 24 hours of symptom onset may be considered for participation in this trial. This is an interventional trial comparing groups receiving medical management or early surgical hematoma evacuation. Identifier: NCT02880878

Electrophysiological Analysis of Epileptogenic Tissue
Investigator: Jodi Smith, MD
Sponsor: The Neurosurgery Foundation at Goodman Campbell
Focus: Translational research study utilizing tissue from seizure surgeries to test medications that may in the future be potential treatments for epilepsy. Pediatric patients undergoing surgical resection for epilepsy may be eligible to participate by donating the tissue removed during their epilepsy surgery.

Hydrocephalus Clinical Research Network (HCRN) Registry
Investigator: Jodi Smith, MD
Sponsor: Unfunded
Focus: This is a multi-center research network seeking to gather information regarding pediatric hydrocephalus and treatments. Pediatric patients undergoing treatment for hydrocephalus may be included.

Long-Term Real-World Outcomes Study on Patients Implanted with a Neurostimulator (REALITY)
Investigator: Derron Wilson, MD
Sponsor: Abbott Medical Devices
Focus: Patients scheduled to receive an implantable Abbott neurostimulation system for chronic pain are eligible for consideration in this study. The goal of the study is to collect safety and effectiveness data on various populations implanted with the systems. Identifier: NCT03876054

SOFia Aspiration System as First Line Technique (SOFAST)
Investigators: Daniel Sahlein, MD; Krishna Amuluru, MD; Andrew DeNardo, MD; John Scott, MD
Sponsor: Microvention
Focus: This is an observational study involving patients undergoing thrombectomy following acute ischemic stroke in the anterior circulation. The goal of the study is to assess functional, imaging and safety outcomes of the SOFIA aspiration catheter.

A Pivotal Study of the Premia Spine TOPS System
Investigators: Eric Potts, MD; John DePowell, MD; Eric Horn, MD; Saad Khairi, MD; Charles Kulwin, MD; Jean-Pierre Mobasser, MD; Shannon McCanna, MD; Richard B. Rodgers, MD;
Sponsor: Premia Spine
Focus: The TOPS System was designed as an alternative to fusion and is a motion preserving posterior spine implant designed to provide dynamic stabilization to a single lumbar spine segment following decompression surgery. The purpose of the trial is to assess whether the TOPS system is more effective than transforaminal lumbar interbody fusion (TLIF) when utilized in a specific population of patients undergoing single level lumbar fusion. Identifier: NCT03012776

Neuromonitoring for Percutaneous Balloon Rhizotomy for Trigeminal Neuralgia
Investigators: Charles Kulwin, MD; Troy Payner, MD
Sponsor: The Neurosurgery Foundation at Goodman Campbell
Focus: This investigator-initiated pilot study explores the use of neuromonitoring during balloon rhizotomy procedures for trigeminal neuralgia. The goal is to determine if neuromonitoring is useful with these procedures and if it can be used to determine the duration of nerve compression needed for individual patients.


Goodman Campbell Brain and Spine physicians publish research results from clinical trials and independent clinical investigations in peer-reviewed biomedical journals. Abstracts, full-text articles and videos can be accessed through the following online resources:

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